- Email Address
- [email protected]
- Research Description
Viruses are simple but fascinating microbes. They are also important for a number of reasons, including that they are major pathogens of humans, animals, and plants. In my lab, we focus on viruses that affect plants, especially grapevines. Ultimately, my research goal is to understand viruses and viral diseases for the betterment of agriculture.
- Research Summary
The ultimate goal of my research is to understand viruses and viral diseases for the betterment of agriculture. This goal is being achieved through investigations using multi-disciplinary approaches including those used in virology, molecular biology, cell biology and biochemistry and through national and international collaborations. Our research involves a number of important viruses that infect plants, which include Grapevine rupestris stem pitting-associated virus (GRSPaV), a ubiquitous and important pathogen of grapes worldwide. Current research directions include: Processing and subcellular localization of the replicase polyprotein of GRSPaV; elucidation of function of the novel Alkylation B (AlkB) domain in the replicase polyprotein of GRSPaV and closteroviruses; structure and cellular localization of viral replication complexes; evolution biology and bio-informatics of major grapevine viruses; development of virus-induced gene-silencing vectors for beneficial applications; and, development and application of highly efficient and economical technologies for the diagnosis of major grapevine viruses.