Keyword: Biochemistry

Robert Harkness

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The Harkness group studies the dynamics of biological molecules toward better understanding how these influence human health and disease. Broadly, our areas of interest include:
(1) How biological macromolecules self-assemble, for example oligomeric protein “machines” that perform reactions as required by the cell, or non-canonical nucleic acid structures such as G-quadruplexes that regulate gene expression.
(2) The mechanisms of biomolecular recognition, e.g. allostery in modulation of the interactions between proteins and ligands.
(3) The relationship between structural dynamics and biological activity.

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Yang Xu

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Research in the Xu laboratory focuses on plant and microalgal lipid metabolism. By applying state-of-the-art approaches in genetics, biochemistry, cellular biology, synthetic biology and biotechnology, we aim to address both fundamental and applied questions in the field. The major research objectives in our research group are to improve our understanding of the mechanisms underlying acyl lipid assembly (e.g. triacylglycerols/oils, galactolipids/photosynthetic membrane lipids, phospholipids/membrane lipids) in photosynthetic organisms and to design lipid biosynthetic pathways to improve agriculture production and produce value-added oils for food, feed, fuel, and materials applications.

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