Research Area: Plant biology

Jennifer Geddes-McAlister

We are interested in characterizing the mechanisms of pathogenesis, adaptation, and survival in fungal and bacterial microbes from a systems biology perspective through mass spectrometry-based quantitative proteomics. Specifically, research in the lab centres around the following areas:
1. Systems biology to elucidate microbial proteome dynamics and interactions;
2. Mechanistic characterization of pathogenic proteins; and
3. Mass spectrometry-based proteomics for drug discovery and repurposing.
Our long-term goals emphasize the utilization of mass spectrometry-based proteomics to fundamentally understand differential microbial adaptation and survival strategies and to integrate a novel systems biology platform for investigation of diverse biological systems.

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Steffen Graether

The main goal of our research program is to understand how the intrinsically disordered late embryogenesis abundant (LEA) proteins are able to protect plants from damage caused by cold, drought and high salinity. Our main focus has been on dehydrins, a group of abiotic stress response proteins that have been shown to protect plants from damage caused by drought and cold. Dehydrins are interesting in that they are composed of a variable number of conserved motifs that appear to have roles in protection of proteins, membranes and DNA from abiotic damage, as well as roles in localization.

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