- Department
- Email Address
- [email protected]
- Research Areas
- Research Keywords
- Research Description
Bacteria are encapsulated by a multi-layered envelope that protects the cell from the environment and performs vital functions crucial for survival. At the Myers lab, we study these bacterial envelopes to inform the development of antimicrobial drugs that could be used to fight bacteria.
- Research Summary
Our current research projects focus on:
- The genetics and enzymology of cell wall glycopolymer degradation and roles in cellular processes including cell division, morphogenesis and the expression of virulence properties.
- The enzymology, structural biology and associated bacterial physiology of lesser-known penicillin-binding proteins, and penicillin-binding protein variants associated with β-lactam resistance.
- The development of activity-independent in vitro platforms to interrogate the flux of xenobiotics across the bacterial cell envelope.- Techniques Used
In the Myers Lab, we employ a diverse array of approaches – biochemical, biophysical, structural, molecular and genetic – to address gaps in the knowledge regarding the biological chemistry of the bacterial cell envelope.
- Locations of international collaborators
Venatorx Pharmaceuticals Inc., MTF Biologics, University of North Texas, Emory University School of Medicine (USA); University of Siena (Italy).
- Links
