- Email Address
- [email protected]
- Research Areas
- Research Keywords
- Research Description
My laboratory studies the complex metabolic interactions between members of the microbiota, microbial crosstalk with the host, and the role of the diverse commensals in colonization resistance.
- Research Summary
Healthy gut microbiota can be disrupted due to antibiotic treatment, intestinal inflammation, or changes in diet. Targeted restoration of the microbiota will require an understanding of how genomic diversity between closely related microbes influences their ability to drive beneficial functions. To address this, our laboratory will use a large collection of whole-genome sequenced isolates to understand how variation between closely related gut isolates alters their ability to prevent pathogen expansion and maintain homeostatic interactions with the mucosal immune system.
- Locations of international collaborators
Memorial Sloan-Kettering Cancer Center, University of Chicago, Weill Cornell Medical College, University of California-Davis (USA); Johann Wolfgang Goethe University (Germany).