Keyword: Toxicology

Sarah Alderman

Current projects include:
- Mechanistic and functional connections between stress and adult neurogenesis in fish
- Effects of aquatic pollutants on fish physiology, morphology, and performance
- Neuroanatomy and regenerative capacity of the hagfish brain
- Quantitative proteomics as a tool for biomarker discovery and novel insights into animal physiology

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Andreas Heyland

Dr. Heyland´┐Żs laboratory uses novel functional genomics approaches to study the endocrine and neuroendocrine systems of aquatic invertebrates. Specifically he investigates the function and evolution of hormonal and neurotransmitter signaling systems in the regulation of development and metamorphosis. His research includes Evolutionary development studies of marine invertebrate metamorphosis, eco-toxicogenomic approached to understand endocrine disruption in aquatic ecosystems and water remediation technologies. These projects are integrated with several national and international collaborations ranging form basic scientific work to industry partnerships.

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Glen Van Der Kraak

My research focuses on the reproductive physiology of fish. We study which hormones affect ovarian follicle development and if there are hallmark responses (changes in hormone biosynthesis, receptor abundance, recruitment of downstream activators) that determine whether an ovarian follicle is destined to mature and ovulate. This research is fundamental to defining spawning success which is a prime measure of reproductive fitness and provides the toolbox that we use to examine the mechanisms by which endocrine disrupting compounds (pharmaceuticals; ammonia) and complex environmental effluents (municipal waste water, pulp mills; oils sands process affected water) affect ovarian physiology.

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Stephen Seah

We are interested in microbial enzymes involved in the steroid and aromatic compounds degradation. These enzymes are important for bioremediation of organic pollutants and are potential targets for development of antibiotics against tuberculosis. In collaboration with Dr. Ting Zhou at Agriculture Agri-food Canada, we are isolating and characterizing enzymes capable of detoxifying the mycotoxins, deoxynivalenol and patulin. These mycotoxins contaminate grains and fruit juices.

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Todd Gillis

Climate change,Environmental health,Animal biology,Human health and performance,Mechanisms of disease

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