Stephen Seah

Email Address
[email protected]
Research Areas
Research Keywords
Research Description

We study enzymes involved in pollutants/mycotoxins degradation and bacterial pathogenesis.

Research Summary

We are interested in microbial enzymes involved in the steroid and aromatic compounds degradation. These enzymes are important for bioremediation of organic pollutants and are potential targets for development of antibiotics against tuberculosis. In collaboration with Dr. Ting Zhou at Agriculture Agri-food Canada, we are isolating and characterizing enzymes capable of detoxifying the mycotoxins, deoxynivalenol and patulin. These mycotoxins contaminate grains and fruit juices.

Techniques Used

Gene cloning, protein expression, enzyme assays, spectroscopy, HPLC, mass spectrometry, X-ray crystallography.

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