David Mutch

Email Address
[email protected]
Research Description

nutritional biochemistry, gene-association studies, gene expression

Research Summary

Dysfunctional lipid metabolism is a key feature of cardiometabolic diseases, such as obesity and type 2 diabetes. My research program has three primary areas of interest:

First, we are using cell and mouse models to determine how omega-3 fats regulate lipid metabolism. We are investigating how omega-3 fats control adipogenesis, as well as lipogenic, lipolytic, and triglyceride synthesis pathways in adipose tissue and liver.

Second, we are studying how different nutrients regulate omega-3 synthesis in the body using both mouse models and human clinical trials.

Third, we are interested to personalize nutrition to improve human cardiometabolic health (PMID: 30472712, 29400991, 28272299). We continue to be active in this area through various national and international collaborations.

Techniques Used

Cell culture
Genetic mouse models
Gas chromatography
Gene expression
Bioinformatics
Human clinical trials
Genotyping
Metabolomics

Lab Equipment

Clermont-Ferrand, France
Tel-Aviv, Israel
Illinois, United States

Links
Scroll to Top